In Vitro Study of ACE (Angiotensin Converting Enzyme) Inhibitory Activity of Pineapple Extract

Khajuria, Mona C.; Upadhyaya, Anvayi N.; Gohel, Rahul S.; Radadiya, B.B.

doi:10.2139/ssrn.3582373

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In Vitro Study of ACE (Angiotensin Converting Enzyme) Inhibitory Activity of Pineapple Extract

Proceedings of the National Conference on Innovations in Biological Sciences (NCIBS) 2020

10 Pages Posted: 23 Apr 2020 Last revised: 8 Jun 2020

See all articles by Mona C. Khajuria

Rahul S. Gohel

Shree M.&N Virani. Science College, Rajkot

B.B. Radadiya

Shree M.&N Virani. Science College, Rajkot

Date Written: April 18, 2020

Abstract

Hypertension is contributory risk factor for cardiovascular disease. RAAS (Renin-Angiotensin-Aldosterone-System) is one of the parts that contribute in maintenance of circulatory strain and electrolytes balance. ACE (Angiotensin Converting Enzyme) is main player of RAAS system. Purpose of the study was to find ACE inhibitory activity of pineapple extract. Various dosages of the extract were utilized and ACE activity was estimated. So as to discover the contributory factor phytochemical examination of pineapple extract was done. Finding of this study shows that significantly (p<0.001) ACE inhibitory activity of pineapple extract in a dose dependent manner. Highest ability to inhibit ACE activity was seen in 500 µl extract of pineapple.

Keywords: ACE inhibitory activity, pineapple, natural ACE inhibitor

Suggested Citation: Suggested Citation

Khajuria, Mona C. and Upadhyaya, Anvayi N. and Gohel, Rahul S. and Radadiya, B.B., In Vitro Study of ACE (Angiotensin Converting Enzyme) Inhibitory Activity of Pineapple Extract (April 18, 2020). Proceedings of the National Conference on Innovations in Biological Sciences (NCIBS) 2020, Available at SSRN: https://ssrn.com/abstract=3582373 or http://dx.doi.org/10.2139/ssrn.3582373